Czech Multicentre Research Database of COPD

Registry of the Czech Pneumological and Phthisiological Society at the CzMA

The COPD registry is a non-interventional multicentre observational prospective database focusing on the collection and analysis of data on real mortality and morbidity in an unselected population of COPD patients. Monitoring is done at the occasion of regular check-ups, followed by retrospective search of data in the documentation, and a record into the registry.

The registry fulfils general objectives of health registries such as monitoring of causes, development, treatment and consequences of a severe disorder, including economic and social impacts. Statistical and scientific analyses of the registry data are focused, in particular, on the assessment of health determiners of the selected patient cohort with the aim to improve health status of the patients.

Primary objective of the project

Monitoring of the real mortality and morbidity in a unselected population of COPD patients

Secondary objectives of the project

Monitoring of the decline in lung function, exercise capacity, symptoms and quality of life over time

Analysis of differences among monitored parameters in patients with different COPD variants (phenotypes)

A short video abstract about the COPD project; published as a part of the paper „Novotná et al. Czech multicenter research database of severe COPD. Int J Chron Obstruct Pulmon Dis 2014, 9: 1265-1274”.

PLEASE NOTE: The data collection related to the MMAS-4 questionnaire was ended on September 30, 2018.

Project background

The chronic obstructive pulmonary disease (COPD) is the occurrence of chronic bronchitis or emphysema, a pair of commonly co-existing diseases of the lungs in which the airways narrow over time. This limits airflow to and from the lungs, causing shortness of breath (dyspnoea). In clinical practice, COPD is defined by its characteristically low airflow on lung function tests. In contrast to asthma, this limitation is poorly reversible and usually gets increasingly worse over time.

Worldwide, COPD ranked as the sixth leading cause of death in 1990. It is projected to become the fourth leading cause of death worldwide by 2030, due to an increase in smoking rates and demographic changes in many countries.

Prognosis of patients is very poor, COPD is a frequent cause of morbidity and mortality. Up-to-date and precise epidemiological data describing the situation in the Czech Republic is currently unavailable.